{"id":17102,"date":"2024-03-28T05:15:08","date_gmt":"2024-03-28T05:15:08","guid":{"rendered":"https:\/\/fipmed.co\/%ec%b5%9c%ea%b3%a0%ec%9d%98-%ea%b2%bd%ea%b5%ac%ec%9a%a9-%ed%95%8d%ed%95%8d-%ec%a0%95%ec%a0%9c-%eb%b0%8f-%ec%ba%a1%ec%8a%90-%ec%b9%98%eb%a3%8c%ec%a0%9c\/"},"modified":"2024-03-28T05:15:08","modified_gmt":"2024-03-28T05:15:08","slug":"%ec%b5%9c%ea%b3%a0%ec%9d%98-%ea%b2%bd%ea%b5%ac%ec%9a%a9-%ed%95%8d%ed%95%8d-%ec%a0%95%ec%a0%9c-%eb%b0%8f-%ec%ba%a1%ec%8a%90-%ec%b9%98%eb%a3%8c%ec%a0%9c","status":"publish","type":"page","link":"https:\/\/fipmed.co\/ko\/%ec%b5%9c%ea%b3%a0%ec%9d%98-%ea%b2%bd%ea%b5%ac%ec%9a%a9-%ed%95%8d%ed%95%8d-%ec%a0%95%ec%a0%9c-%eb%b0%8f-%ec%ba%a1%ec%8a%90-%ec%b9%98%eb%a3%8c%ec%a0%9c\/","title":{"rendered":"FIP\ub97c \uc704\ud55c \ucd5c\uace0\uc758 \uacbd\uad6c\uc6a9 \uc758\uc57d\ud488 – FIP \uc815\uc81c \ubc0f \ucea1\uc290"},"content":{"rendered":"

\uc77c\ubc18\uc801\uc73c\ub85c \uc8fc\uc0ac\uac00 \uacbd\uad6c\uc6a9 GS-441524\ubcf4\ub2e4 FIP \uce58\ub8cc\uc5d0 \ub354 \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc9c0\ub9cc, \ub9ce\uc740 \uace0\uc591\uc774 \ubcf4\ud638\uc790\ub4e4\uc740 \uc8fc\uc0ac\ub85c \uc778\ud55c \uc7a0\uc7ac\uc801\uc778 \ubd88\ud3b8\ud568\uc744 \ud53c\ud558\uae30 \uc704\ud574 \uacbd\uad6c\uc6a9 \uc635\uc158\uc744 \uc120\ud0dd\ud569\ub2c8\ub2e4. \uc77c\ubd80 \uace0\uc591\uc774\ub294 \uc7a5\uae30\uac04\uc758 \uce58\ub8cc \ud6c4 \ubd88\ud3b8\ud568\uc744 \ub290\ub07c\uac70\ub098 \uc8fc\uc0ac\ub97c \uc2eb\uc5b4\ud560 \uc218 \uc788\uc73c\uba70, \uc2dc\uc220\uc5d0 \uac15\ub825\ud558\uac8c \ubc18\ub300\ud558\ub294 \uace0\uc591\uc774\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc57d\ubb3c\uc758 \uc0b0\uc131\uc73c\ub85c \uc778\ud574 \uc8fc\uc0ac \ubd80\uc704\uc5d0 \uc5fc\uc99d\uc774 \uc0dd\uae38 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc0c1\ud669\uc5d0\uc11c\ub294 \uacbd\uad6c\uc6a9 \ucea1\uc290\uc774\ub098 FIP \uc815\uc81c\ub97c \uc8fc\uc0ac \ub300\uc6a9\uc73c\ub85c \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacbd\uad6c \ud22c\uc5ec \uc2dc \uc57d\ubb3c \ub0b4\uc131\uc5d0 \ub300\ud574 \uac71\uc815\ud560 \ud544\uc694\uac00 \uc5c6\uc2b5\ub2c8\ub2e4. GS-441524\uc758 \uc2b5\uc2dd \ubc0f \uac74\uc2dd FIP \uce58\ub8cc\uc5d0 \ub300\ud55c \ud6a8\uacfc\ub294 \ubcf5\uc6a9 \ud615\ud0dc\uc5d0 \uad00\uacc4\uc5c6\uc774 \uc77c\uad00\ub418\uac8c \ub098\ud0c0\ub0a9\ub2c8\ub2e4.<\/p>\n

\ud604\uc7a5\uc5d0\uc11c FIP\ub97c \uce58\ub8cc\ud558\uae30 \uc704\ud55c GS-441524\uc758 \uccab \ubc88\uc9f8 \ud14c\uc2a4\ud2b8\uc5d0\uc11c\ub294 \ud53c\ubd80 \uc544\ub798\uc5d0 \uc8fc\uc0ac\ud588\uc2b5\ub2c8\ub2e4. \uc815\ub9e5 \uc8fc\uc0ac\uc640 \ud53c\ud558 \uc8fc\uc0ac \ubaa8\ub450 24\uc2dc\uac04 \uc774\uc0c1 \ubc14\uc774\ub7ec\uc2a4\ub97c \uc5b5\uc81c\ud558\ub294 \uc218\uc900\uc73c\ub85c \uc720\uc9c0\ub418\ub294 \ub192\uc740 \ud608\uc911 \ub18d\ub3c4\ub97c \uc0dd\uc131\ud588\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc790\ub4e4\uc740 \ub610\ud55c \uc57d\ubb3c\uc744 \uacbd\uad6c\ub85c \ud22c\uc5ec\ud558\uba74 \ud608\uc911 \ub18d\ub3c4\uac00 \uc0c1\uc2b9\ud558\uc9c0\ub9cc, \ud53c\ud558 \ubc0f \uc815\ub9e5 \uacbd\ub85c\uc5d0\uc11c \ubcf4\uc774\ub294 \ucd5c\uace0 \uc218\uc900\uc758 \uc57d 40% \uc815\ub3c4\ub9cc \uc870\uae08 \ud6c4\uc5d0 \uc0c1\uc2b9\ud55c\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4(Pedersen NC, \uac1c\uc778 \ub370\uc774\ud130, 2018). \uadf8\ub7ec\ub098 \uc721\ub958\uc640 \uc2dd\ubb3c\uc744 \ubaa8\ub450 \uba39\ub3c4\ub85d \uc9c4\ud654\ud55c \uc7a5\uc774 \uae34 \uac1c\ub294 \uba39\uc774\ub97c \ud1b5\ud574 GS441524\uc758 \ucd5c\ub300 85%\ub97c \uc12d\ucde8\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4 [1, 5]. \uad6c\uac15 \ud761\uc218 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc885\uc885 \uac1c\ub97c \uc0ac\ub78c\uc758 \ub300\uc6a9\ud488\uc73c\ub85c \uc0ac\uc6a9\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc0ac\ub78c\uc758 \uad6c\uac15 \ud761\uc218\uc728\ub3c4 \uace0\uc591\uc774\ubcf4\ub2e4 \ub192\uc744 \uac00\ub2a5\uc131\uc774 \ub192\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n

\uadf8\ub798\uc11c \ud53c\ud558 \ud22c\uc5ec \ubc29\uc2dd\uc740 \uc0ac\uc6a9\uc774 \uac04\ud3b8\ud558\uace0 \ud608\uc911 \ub18d\ub3c4\uac00 \ub192\uae30 \ub54c\ubb38\uc5d0 \ud604\uc7a5\uc5d0\uc11c \uace0\uc591\uc774\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uc2e4\ud5d8\uc5d0 \uc120\ud0dd\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

GS-441524\uc758 \uc911\uad6d \ud310\ub9e4\uc790\ub294 \uacf5\uac1c\ub41c \uc784\uc0c1\uc2dc\ud5d8\uc758 \ud76c\uc11d\uc81c, \uc57d\ubb3c \ub18d\ub3c4 \ubc0f \ud53c\ud558 \ud22c\uc5ec \ubc29\ubc95\uc744 \ubaa8\ubc29\ud588\uc2b5\ub2c8\ub2e4. \uadf8 \ud6c4, \uadf8\ub4e4\uc740 \uc57d\ubb3c\uc744 \uc5f0\uad6c\ud558\uc5ec \uc54c\uc57d \ud615\ud0dc\ub85c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc911\uad6d\uc758 \uc5f0\uad6c\uc790\ub4e4\uc740 \uacbd\uad6c\uc6a9 \ubc84\uc804\uc5d0 \uc57d\ubb3c\uc744 \ub354 \ub9ce\uc774 \ud568\uc720\ud558\ub294 \uac83\ub9cc\uc73c\ub85c\ub3c4 GS-441524\uc758 \ud608\uc911 \ub18d\ub3c4\ub97c \ud6a8\uacfc\uc801\uc73c\ub85c \ub192\uc77c \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8 \ud6c4 \ub2e4\ub978 \ud68c\uc0ac\uc5d0\uc11c\ub3c4 \uacbd\uad6c \ubcf5\uc6a9\uc774 \uac00\ub2a5\ud55c \uc790\uccb4 \ubc84\uc804\uc758 GS-441524\ub97c \ucd9c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. \uc18c\ube44\uc790\ub294 \uc9c0\uae08 \ubc14\ub85c \ucea1\uc290\uacfc \uc815\uc81c\ub97c \uad6c\ub9e4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub77c\ubca8\uc5d0\ub294 \uc5ec\ub7ec \uac00\uc9c0 \uc778\uae30 \uc788\uace0 \uc548\uc804\ud55c \ud654\ud559\ubb3c\uc9c8\uacfc \uc758\ub8cc\uc6a9 \ud5c8\ube0c\uac00 \uc131\ubd84\uc73c\ub85c \uba85\uc2dc\ub418\uc5b4 \uc788\uc9c0\ub9cc, GS-441524\ub294 \uadf8 \uc911 \ud558\ub098\uac00 \uc544\ub2d9\ub2c8\ub2e4. \uc138\uad00 \uc9c1\uc6d0\ub4e4\uc740 \uc544\ub9c8 \uc774\uac83\uc744 \uc790\uc138\ud788 \ubcf4\uc9c0 \uc54a\uc744 \uac83\uc785\ub2c8\ub2e4. GS-441524\ub294 \ub2e4\ub978 \uc131\ubd84\uc774 \ubb34\uc5c7\uc774\ub4e0 \ubaa8\ub4e0 \uad6c\uac15\uc6a9\ud488\uc758 \ud65c\uc131\uc81c\uc785\ub2c8\ub2e4. \uc124\ud558 \uc81c\ud488\uc744 \ud310\ub9e4\ud558\ub294 \ud68c\uc0ac\ub294 GS-441524\uac00 \uc5bc\ub9c8\ub098 \ub4e4\uc5b4 \uc788\ub294\uc9c0 \ub9d0\ud558\uc9c0 \uc54a\uc9c0\ub9cc \uc57d\ubb3c\uc774 \ud53c\ubd80 \uc544\ub798\uc5d0 \ud22c\uc5ec\ub418\ub294 \uacbd\uc6b0 \ud544\uc694\ud55c \uac83\ubcf4\ub2e4 \ud6e8\uc52c \ub354 \ub9ce\uc740 \uc591\uc774\ub77c\ub294 \uac83\uc740 \ubd84\uba85\ud569\ub2c8\ub2e4.<\/p>\n

\uc810\uc810 \ub354 \ub9ce\uc740 \ubc18\ub824\ub3d9\ubb3c \ubcf4\ud638\uc790\uc640 \uc218\uc758\uc0ac\uac00 \uacbd\uad6c\uc6a9 GS-441524\ub97c \uce58\ub8cc\uc758 \uc77c\ubd80 \ub610\ub294 \uc804\ubd80\ub85c \uc0ac\uc6a9\ud558\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \uc9c0\ub09c 2\ub144 \ub3d9\uc548 \uacbd\uad6c\uc6a9 GS-441524 \uc81c\ud488\uc758 \ud488\uc9c8\uc740 \ub192\uc544\uc9c4 \ubc18\uba74 \uac00\uaca9\uc740 \uc11c\uc11c\ud788 \ub0ae\uc544\uc84c\uc2b5\ub2c8\ub2e4. \uc8fc\uc0ac \ubd80\uc704 \ubc18\uc751\uc758 \ubb38\uc81c\uc640 GS-441524\uc758 \uacbd\uad6c \uc81c\uc81c\uac00 \ub354 \uc798 \uc791\ub3d9\ud55c\ub2e4\ub294 \uc0ac\uc2e4 \ub54c\ubb38\uc5d0 \uad6c\uac15 \uce58\ub8cc\uac00 \ub354 \ub300\uc911\ud654\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc810\uc810 \ub354 \ub9ce\uc740 \uace0\uc591\uc774\uac00 \uce58\ub8cc\uc758 \uc77c\ubd80 \ub610\ub294 \uc804\ubd80\ub97c \uacbd\uad6c \ubcf5\uc6a9\ud558\ub294 \uc57d\ubb3c\ub85c \uce58\ub8cc\ub97c \ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

FIP \uc815\uc81c \ub300 \ucea1\uc290: \uad6c\uc131 \ubc0f \ubcf5\uc6a9\ub7c9<\/h1>\n

\uacbd\uad6c\uc6a9 GS-441524\ub294 \ud761\uc218\uc728 \uc190\uc2e4\uc744 \ubcf4\uc644\ud558\uae30 \uc704\ud574 \ud65c\uc131 \uc131\ubd84\uc778 GS441524\uac00 \ud6e8\uc52c \ub354 \ub9ce\uc774 \ud568\uc720\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. \uc798 \uc54c\ub824\uc9c4 \uacbd\uad6c\uc6a9 \uc81c\ud488\uc740 \ubaa8\ub450 \uc54c\uc57d\uc785\ub2c8\ub2e4. \ud558\uc9c0\ub9cc FIPMed\uc758 \uc815\uc81c\ub294 \ud06c\uae30\uac00 \uc791\uc544 \uc12d\ucde8\ud558\uae30\uac00 \ub354 \uc27d\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uacbd\uad6c\uc6a9 \uc57d\ud488\uc740 \uc561\uccb4 \ub610\ub294 \ubd84\ub9d0\ub85c \ucc44\uc6cc\uc9c4 FIP \ucea1\uc290\ub85c, \uace0\uc591\uc774\uac00 \uc774\ub97c \uae68\ubb3c\uba74 \ub0b4\ubd80\uc758 \uc57d\uc774 \uc190\uc2e4\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uace0\uc591\uc774\uac00 \uc54c\uc57d\uc744 \ub72f\uc5b4 \uba39\uc73c\uba74 \ub098\uc05c \ubc18\uc751\uc744 \ubcf4\uc774\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc54c\uc57d\uc774\ub098 \uc815\uc81c\uc758 \ubcf5\uc6a9 \ubc29\ubc95\uc740 \ubaa8\ub4e0 \uacbd\uad6c\uc81c \uc720\ud615\uc5d0 \ub300\ud574 \ub3d9\uc77c\ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc57d\uc744 \ud22c\uc5ec\ud558\uae30 \uc804\ud6c4 30\ubd84 \ub3d9\uc548\uc740 \uc544\ubb34\uac83\ub3c4 \uba39\uac70\ub098 \ub9c8\uc2dc\uc9c0 \uc54a\ub294 \uac83\uc774 \uac00\uc7a5 \uc88b\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uace0\uc591\uc774\ub294 \uc791\uc740 \uac04\uc2dd\uc744 \uc8fc\uba74 \uae30\uaebc\uc774 \uba39\uc744 \uc218 \uc788\uc73c\uba70, \uce04\ub8e8\uc640 \uac19\uc774 \ub36e\uac1c \uac04\uc2dd\uc744 \uc811\uc2dc\uc5d0 \ub2f4\uc544\uc8fc\uba74 \ub9ce\uc740 \uace0\uc591\uc774\uac00 \uba39\uc2b5\ub2c8\ub2e4.<\/p>\n

\uacbd\uad6c\uc6a9 \ucea1\uc290\uacfc \uc54c\uc57d \ubaa8\ub450 \ub611\uac19\uc774 \ud6a8\uacfc\uc801\uc774\uc9c0\ub9cc, \uc77c\ubc18\uc801\uc73c\ub85c \ucea1\uc290\uc744 \ubcf5\uc6a9\ud558\ub294 \uac83\uc774 \uc54c\uc57d\ubcf4\ub2e4 \ub354 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \ucea1\uc290\uc740 \ud06c\uae30\uac00 \ucee4\uc11c \uace0\uc591\uc774\uac00 \uc27d\uac8c \uc0bc\ud0a4\uae30 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \ubd84\ub9d0 \ud615\ud0dc\ub97c \uc815\uc81c\ub85c \uc555\ucd95\ud558\ub824\uba74 \ub354 \ub9ce\uc740 \uc0dd\uc0b0 \ub2a5\ub825\uc774 \ud544\uc694\ud558\uc9c0\ub9cc, \ubc31\ub3c4\uc5b4 \uc544\ub9c8\ucd94\uc5b4 \uc0dd\uc0b0\uc740 \ubd84\ub9d0\uc744 \ucea1\uc290\uc5d0 \ub123\ub294 \ub370 \uc0ac\ub78c\uc758 \ub178\ub3d9\ub825\uc744 \uc0ac\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n

FIPMED \uacbd\uad6c\uc6a9 \uc54c\uc57d\uc740 \uc2dc\uc911\uc5d0 \ub098\uc640 \uc788\ub294 \uc54c\uc57d\uc5d0 \ube44\ud574 \ud06c\uae30\uac00 \uc791\uc9c0\ub9cc \ud761\uc218 \uac00\ub2a5\ud55c GS441524\uc758 \uc591\uc774 \ub9ce\uc2b5\ub2c8\ub2e4. \uc2dc\uc911\uc5d0 \ud310\ub9e4\ub418\ub294 5mg \uc81c\ud488\uacfc \ub2ec\ub9ac 30mg \ubc0f 40mg \ub18d\ub3c4\ub85c \ud310\ub9e4\ub418\uba70, \ub3d9\uc77c\ud55c \ud6a8\uacfc\ub97c \uc5bb\uc73c\ub824\uba74 \uc5ec\ub7ec \uc815\uc744 \ubcf5\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4. \ud06c\uae30\uac00 \uc791\uc544 \ub300\ubd80\ubd84\uc758 \uc0c1\ud669\uc5d0\uc11c \uc27d\uac8c \uad00\ub9ac\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

FIP \ud0dc\ube14\ub9bf \ube44\uc6a9<\/h1>\n

\uc9c0\ub09c 1\ub144 \ub3d9\uc548 \uacbd\uad6c\uc6a9 GS\uc758 \uac00\uaca9\uc774 \ub9ce\uc774 \ub0b4\ub824\uac14\uc2b5\ub2c8\ub2e4. \uac00\uaca9\uc5d0 \uad00\ud574\uc11c\ub294 \uacbd\uad6c\uc6a9 GS-441524\uac00 \uc8fc\uc0ac\uc81c\ubcf4\ub2e4 20~40% \ub354 \ube44\uc2f8\uc9c0\ub9cc FIPMed\uc758 \uc815\uc81c\ub294 \uc2dc\uc7a5\uc5d0\uc11c \uac00\uc7a5 \uc800\ub834\ud558\uace0 \uc8fc\uc0ac\uc81c\uc640 \uac70\uc758 \ube44\uc2b7\ud55c \uac00\uaca9\uc785\ub2c8\ub2e4.<\/p>\n

\uc785\uc73c\ub85c \ud558\ub294 \uac83\uacfc \uc0f7\uc73c\ub85c \ud558\ub294 \uac83\uc774 \ub2e4\ub978 \uc810<\/h1>\n

\uacbd\uad6c\uc6a9 GS-441524\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uc774\ubbf8 \uad6c\ud1a0\ub098 \uc5ed\ub958, \uc124\uc0ac\ub97c \ud558\uace0 \uc788\ub294 \uace0\uc591\uc774\uc5d0\uac8c\ub294 \uc801\ud569\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc0ac\ub78c\ub4e4\uc740 \uc18c\ud654\uae30 \uc9c8\ud658\uc774 \uc2ec\ud55c \uace0\uc591\uc774\uc5d0\uac8c \ubb38\uc81c\uac00 \uc0ac\ub77c\uc9c8 \ub54c\uae4c\uc9c0 \uc8fc\uc0ac\ub97c \ub193\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4. \ub610\ud55c GS-441524\uc758 \ud53c\ud558 \ud22c\uc5ec\ub294 \uacbd\uad6c \ud22c\uc5ec\ubcf4\ub2e4 \ub354 \uc548\uc815\uc801\uc785\ub2c8\ub2e4. \uc774\uac83\uc740 \uc885\uc885 \ub9e4\uc6b0 \uc544\ud504\uace0 \ubd88\uc548\uc815\ud55c \uace0\uc591\uc774\uc758 \ucd08\uae30 \uce58\ub8cc\uc5d0 \ub9e4\uc6b0 \uc911\uc694\ud55c \uc694\uc18c\uc785\ub2c8\ub2e4. \uace0\uc591\uc774\uc5d0\uac8c GS-441524 \uc8fc\uc0ac\ub97c \uacc4\uc18d \ub9de\ucd9c\uc9c0 \uc5ec\ubd80\ub97c \uacb0\uc815\ud560 \ub54c\ub294 \uc8fc\uc778\uc774 \uc8fc\uc0ac\ub97c \uc5bc\ub9c8\ub098 \uc798 \ub9de\ucd9c \uc218 \uc788\ub294\uc9c0, \uace0\uc591\uc774\uac00 \ud1b5\uc99d\uc5d0 \uc5bc\ub9c8\ub098 \uc775\uc219\ud574\uc9c8 \uc900\ube44\uac00 \ub418\uc5b4 \uc788\ub294\uc9c0, \uc8fc\uc0ac \ubd80\uc704 \uc5fc\uc99d\uc774 \uc5bc\ub9c8\ub098 \uc790\uc8fc \ub098\ud0c0\ub098\ub294\uc9c0\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \uc774\ub7f4 \ub54c \uacbd\uad6c\uc6a9 \uc57d\uc740 \uc885\uc885 \uc8fc\uc778\uacfc \uace0\uc591\uc774 \ubaa8\ub450\uc5d0\uac8c \uc88b\uc740 \ud734\uc2dd\ucc98\uac00 \ub429\ub2c8\ub2e4.<\/p>\n

\uacbd\uad6c\uc6a9 GS-441524\ub294 FIP \uce58\ub8cc\uc81c\ub85c\uc11c \uc5bc\ub9c8\ub098 \ud6a8\uacfc\uc801\uc77c\uae4c\uc694?<\/h1>\n

\uc801\uc808\ud55c \uc2dc\uac04\uacfc \uc6a9\ub7c9\uc73c\ub85c \ud22c\uc5ec\ud558\uba74 \uacbd\uad6c\uc6a9 FIP \uce58\ub8cc\ub294 \uace0\uc591\uc774 \uac10\uc5fc\uc131 \ubcf5\ub9c9\uc5fc\uc744 \uce58\ub8cc\ud558\ub294 \ub370 \ud53c\ud558 \uc8fc\uc0ac\ub9cc\ud07c \ud6a8\uacfc\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubc18\uba74, FIP \uce58\ub8cc \uc804\ubb38\uac00\ub4e4\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uacbd\uad6c \uce58\ub8cc\ub97c \ubc1b\uc740 \uace0\uc591\uc774\uac00 \uc804\uccb4 \uce58\ub8cc \uacfc\uc815\uc5d0\uc11c \uc8fc\uc0ac\ub85c \uce58\ub8cc\ubc1b\uc740 \uace0\uc591\uc774\uc5d0 \ube44\ud574 \uc7ac\ubc1c \uac00\ub2a5\uc131\uc774 \ub354 \ub192\ub2e4\ub294 \ub370 \ub3d9\uc758\ud569\ub2c8\ub2e4. \uacbd\uad6c\uc6a9 \ucea1\uc290\uacfc \uc54c\uc57d\uc740 \uc2e0\uacbd\ud559\uc801 \ud615\ud0dc\uc758 FIP\uac00 \uc788\uac70\ub098 \uad6c\ud1a0\ub098 \uc124\uc0ac\ub97c \uc790\uc8fc \ud558\ub294 \uace0\uc591\uc774\uc5d0\uac8c\ub294 \ucd5c\uc801\uc758 \uce58\ub8cc\uac00 \ub418\uc9c0 \uc54a\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud604\uc7ac \uc8fc\uc0ac \ub610\ub294 \uacbd\uad6c\uc6a9 FIP \uce58\ub8cc\uc640 \uad00\ub828\ub41c \ubd80\uc791\uc6a9\uc740 \ubcf4\uace0\ub41c \ubc14 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc77c\ubd80 \uace0\uc591\uc774\ub294 \uccab \ubc88\uc9f8 \uce58\ub8cc\uc81c\ub85c GS-441524\ub97c \uacbd\uad6c \ubcf5\uc6a9\ud588\uc744 \ub54c \ubc18\uc751\uc774 \uc88b\uc9c0 \uc54a\uc558\uac70\ub098 \uc8fc\uc0ac\uc81c\uc5d0\uc11c \uc54c\uc57d\uc73c\ub85c \uc804\ud658\ud588\uc744 \ub54c \uc7ac\ubc1c\ud55c \uc0ac\ub840\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc0ac\ub840\uc5d0\uc11c\ub294 \uace0\uc591\uc774\uc5d0\uac8c \uac19\uc740 \uc591\uc758 GS-441524\ub97c \uacbd\uad6c \ud22c\uc5ec\ud558\uc5ec \uc8fc\uc0ac\uc5d0 \uc798 \ubc18\uc751\ud558\uc9c0 \uc54a\ub358 \uc9c8\ubcd1\uc774 \uc644\uce58\ub41c \uacbd\uc6b0\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 \ubc14\uc774\ub7ec\uc2a4\uac00 \ub2e4\ub978 \uc57d\ubb3c\uc5d0 \ub0b4\uc131\uc744 \uac16\uac8c \ub41c \uacbd\uc6b0, \uc2e0\uacbd FIP \uc9c8\ud658 \uce58\ub8cc\uc5d0 \ud544\uc694\ud55c \uc815\ud655\ud55c \uc591\uc5d0 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub294 \uc8fc\uc0ac\uc81c \ud615\ud0dc\uc758 GS-441524\ub97c \uad8c\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n

 <\/p>\n

GS-441524 \ubc0f GS-441524\uc640 \uad00\ub828\ub41c \ub274\ud074\ub808\uc624\uc2dc\ub4dc\uc758 \uc704\uc7a5\uad00 \ud761\uc218\uc5d0 \uad00\ud55c \ucc38\uace0 \ubb38\ud5cc \uc5f0\uad6c<\/p>\n

1. \ud1a0\ub9c8\uc2a4 L. \ub818\ub370\uc2dc\ube44\ub974\uc758 \uc804\uad6c\uccb4\uac00 COVID-19\uc5d0 \ub300\ud55c \uce58\ub8cc \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.
\nhttps:\/\/www.news-medical.net\/news\/20210209\/A-precursor-to-remdesivir-showstherapeuticpotential-for-COVID-19.aspx.<\/p>\n

2. \ud398\uc778\ud130 GR, \ubcf4\uc6ec RA, \ube14\ub8e8\ubc0d GR \ub4f1 2. \uc758 \uc608\ubc29 \ubc0f \uce58\ub8cc \ud65c\ub3d9\uc740
\n\ube44\uac15 \ub0b4 \ubca0\ub124\uc218\uc5d8\ub77c \ub9d0\uc758 \uc950 \ubaa8\ub378\uc5d0\uc11c \uad11\ubc94\uc704 \ud65c\uc131 \ub9ac\ubcf4\ub274\ud074\ub808\uc624\uc0ac\uc774\ub4dc \uc720\uc0ac\uccb4
\n\ub1cc\uc5fc \ubc14\uc774\ub7ec\uc2a4 \uac10\uc5fc. 2019;171:104597.
\ndoi:10.1016\/j.antiviral.2019.104597<\/p>\n

\uacbd\uad6c \ud22c\uc5ec \ud6c4 EIDD-1931\uc740 \ud608\uc7a5 T-\ucd5c\ub300\uce58\uc5d0\uc11c \uc54c \uc218 \uc788\ub4ef\uc774 \ube60\ub974\uac8c \ud761\uc218\ub429\ub2c8\ub2e4.
\n0.5\uc2dc\uac04\uc5d0\uc11c 1.0\uc2dc\uac04 \uc0ac\uc774\ub85c \ub178\ucd9c\uc774 \ub192\uc74c(C-ma-x\uac12\uc740 30~40\u03bcM \ubc94\uc704)
\n\uc6a9\ub7c9\uc5d0 \ub530\ub77c \ub2e4\ub974\uc9c0\ub9cc \uc6a9\ub7c9\uc5d0 \ube44\ub840\ud558\ub294 \uac83\ubcf4\ub2e4 \ud6e8\uc52c \uc801\uc2b5\ub2c8\ub2e4. \uad00\ucc30
\n\uc6a9\ub7c9\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c \uc0dd\uccb4 \uc774\uc6a9\ub960\uc774 \uac10\uc18c\ud558\ub294 \uac83\uc740 \ud761\uc218 \ub2a5\ub825\uc758 \uc81c\ud55c\uc744 \ub098\ud0c0\ub0bc \uc218 \uc788\uc2b5\ub2c8\ub2e4.
\n\ud604\uc0c1\uc740 \ub2e4\ub978 \ub274\ud074\ub808\uc624\uc2dc\ub4dc\uc5d0\uc11c \ubcf4\uace0\ub41c \ubc14 \uc788\uc2b5\ub2c8\ub2e4(\ub4dc \ubbf8\ub780\ub2e4 \uc678, 1981). EIDD-1931,
\n\ub294 \ub300\ubd80\ubd84\uc758 \ub0b4\uc778\uc131 \ub274\ud074\ub808\uc624\uc2dc\ub4dc \ubc0f \uc678\uc778\uc131 \ub274\ud074\ub808\uc624\uc2dc\ub4dc \uc720\uc0ac\uccb4\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c \uadf9\uc131\uc774 \ub9e4\uc6b0 \uac15\ud569\ub2c8\ub2e4,
\n\uce5c\uc218\uc131 \ubd84\uc790(cLog P = -2.2)\ub85c\uc11c \uae30\ub2a5\uc801 \uc218\uc1a1\uccb4\uac00 \ud544\uc694\ud560 \uac00\ub2a5\uc131\uc774 \ub192\uc2b5\ub2c8\ub2e4.
\n\uc138\ud3ec\ub9c9\uc744 \uad50\ucc28\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc758\uc874\uc131\uc740 \ub2e4\uc74c\uacfc \uac19\uc740 \uc6a9\ub7c9 \uc81c\ud55c\uc744 \uc124\uba85\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.
\nCD-1 \ub9c8\uc6b0\uc2a4\ub97c \uc0ac\uc6a9\ud55c \uc57d\ub3d9\ud559 \uc5f0\uad6c\ub97c \uc218\ud589\ud588\uc2b5\ub2c8\ub2e4. \uc774\uc804 \ubcf4\uace0\uc11c\uc5d0\uc11c\ub3c4 \ub274\ud074\ub808\uc624\uc2dc\ub4dc
\n\ub9c8\uc6b0\uc2a4 \uc7a5 \uc0c1\ud53c \uc138\ud3ec\ub85c\uc758 \ud761\uc218\ub294 \uc8fc\ub85c \ub098\ud2b8\ub968 \uc758\uc874\uc131\uc5d0 \uc758\ud574 \ub9e4\uac1c\ub429\ub2c8\ub2e4.
\n\ub18d\ucd95 \ub274\ud074\ub808\uc624\uc2dc\ub4dc \uc218\uc1a1\uccb4(Cass et al., 1999; Vijayalakshmi and Belt, 1988).<\/p>\n

3. Cass, C.E., Young, J.D., Baldwin, S.A., Cabrita, M.A., Graham, K.A., Griffiths, M.,Jennings,
\nL.L., \ub9e5\ud0a4, \uc81c\uc774\uc54c, \uc751, \uc5d0\uc774\uc5e0, \ub9ac\uccbc, \uc5e0\ub354\ube14\uc720, \ube44\ucee4\uc2a4, \uc5e0\uc5d0\ud504, \uc57c\uc624, \uc5d0\uc2a4\uc640\uc774, 1999.\ub274\ud074\ub808\uc624\uc0ac\uc774\ub4dc.
\n\ud3ec\uc720\ub958 \uc138\ud3ec\uc758 \uc218\uc1a1\uccb4. Pharm. Biotechnol. 12313-12352<\/p>\n

4. de Miranda, P., Krasny, H.C., Page, D.A., Elion, G.B., 1981. \uc544\uc2dc\ud074\ub85c\ubc84\uc758 \uc131\ud5a5
\n\ubb34\uad00\uc2ec\ud55c \uc885. J. Pharmacol. Exp. Ther. 219 (2), 309-315<\/p>\n

5. \ube44\uc790\uc57c\ub77d\uc26c\ubbf8, D., \ubca8\ud2b8, J.A., 1988. \ub9c8\uc6b0\uc2a4\uc5d0\uc11c \ub098\ud2b8\ub968 \uc758\uc874\uc131 \ub274\ud074\ub808\uc624\uc2dc\ub4dc \uc218\uc1a1
\n\uc7a5 \uc0c1\ud53c \uc138\ud3ec. \uc11c\ub85c \ub2e4\ub978 \uae30\uc9c8 \ud2b9\uc131\uc744 \uac00\uc9c4 \ub450 \uac00\uc9c0 \uc804\uc1a1 \uc2dc\uc2a4\ud15c. Biol.
\nChem. 263 (36), 19419-19423.<\/p>\n

6. \uc580 VC, \uce74\ub4dc\uce74 S, \uc544\uc11c K, \uc560\ud06c\ub85c\uc774\ub4dc JJ, \uc870\uc9c0\uc6b0 DK, \ubbac\ub7ec FL. \uacbd\uad6c\uc6a9 \uc57d\ub3d9\ud559
\n\uac1c\uc5d0 GS-441524\ub97c \ud22c\uc5ec\ud588\uc2b5\ub2c8\ub2e4. bioRxiv, \ub3c4\uc774: https:\/\/doi.org\/10.1101\/2021.02.04.429674<\/p>\n

7. https:\/\/ccah.vetmed.ucdavis.edu\/<\/p>\n","protected":false},"excerpt":{"rendered":"

\uc77c\ubc18\uc801\uc73c\ub85c \uc8fc\uc0ac\uac00 \uacbd\uad6c\uc6a9 GS-441524\ubcf4\ub2e4 FIP \uce58\ub8cc\uc5d0 \ub354 \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc9c0\ub9cc, \ub9ce\uc740 \uace0\uc591\uc774 \ubcf4\ud638\uc790\ub4e4\uc740 \uc8fc\uc0ac\ub85c \uc778\ud55c \uc7a0\uc7ac\uc801\uc778 \ubd88\ud3b8\ud568\uc744 \ud53c\ud558\uae30 \uc704\ud574 \uacbd\uad6c\uc6a9 \uc635\uc158\uc744 \uc120\ud0dd\ud569\ub2c8\ub2e4. \uc77c\ubd80 \uace0\uc591\uc774\ub294 \uc7a5\uae30\uac04\uc758 \uce58\ub8cc \ud6c4 \ubd88\ud3b8\ud568\uc744 \ub290\ub07c\uac70\ub098 \uc8fc\uc0ac\ub97c \uc2eb\uc5b4\ud560 \uc218 \uc788\uc73c\uba70, \uc2dc\uc220\uc5d0 \uac15\ub825\ud558\uac8c \ubc18\ub300\ud558\ub294 \uace0\uc591\uc774\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc57d\ubb3c\uc758 \uc0b0\uc131\uc73c\ub85c \uc778\ud574 \uc8fc\uc0ac \ubd80\uc704\uc5d0 \uc5fc\uc99d\uc774 \uc0dd\uae38 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc0c1\ud669\uc5d0\uc11c\ub294 \uacbd\uad6c\uc6a9 \ucea1\uc290\uc774\ub098 […]<\/p>\n","protected":false},"author":1,"featured_media":16956,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_glsr_average":0,"_glsr_ranking":0,"_glsr_reviews":0,"footnotes":""},"categories":[644],"tags":[],"_links":{"self":[{"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/pages\/17102"}],"collection":[{"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/comments?post=17102"}],"version-history":[{"count":0,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/pages\/17102\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/media\/16956"}],"wp:attachment":[{"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/media?parent=17102"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/categories?post=17102"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fipmed.co\/ko\/wp-json\/wp\/v2\/tags?post=17102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}