<\/p>\n
FIP je sp\u00f4soben\u00e1 v\u00edrusom, tak\u017ee choroba m\u00f4\u017ee zosta\u0165 latentn\u00e1 (neakt\u00edvna) v organizme infikovanej ma\u010dky aj nejak\u00fd \u010das po prvej lie\u010dbe. K relapsu FIP m\u00f4\u017ee d\u00f4js\u0165 aj nieko\u013eko mesiacov alebo t\u00fd\u017ed\u0148ov po ukon\u010den\u00ed lie\u010dby, ak sa v\u00edrus reaktivuje. Okrem toho sa zistilo, \u017ee relapsy s\u00fa \u010dastej\u0161ie u ma\u010diek s neurologick\u00fdmi pr\u00edznakmi FIP v porovnan\u00ed s in\u00fdmi formami ochorenia, \u010do ich rob\u00ed obzvl\u00e1\u0161\u0165 zranite\u013en\u00fdmi vo\u010di tomuto probl\u00e9mu. V pr\u00edpade dobre zisten\u00fdch pr\u00edpadov zah\u0155\u0148aj\u00facich infekcie o\u010d\u00ed, mozgu a chrbtice m\u00f4\u017ee by\u0165 na \u00fapln\u00e9 vyrie\u0161enie a zotavenie z FIP potrebn\u00e1 minim\u00e1lne 12-t\u00fd\u017ed\u0148ov\u00e1 lie\u010dba. <\/p>\n
Imunosupres\u00edva s\u00fa lieky, ktor\u00e9 sa zvy\u010dajne predpisuj\u00fa na zn\u00ed\u017eenie po\u0161kodenia sp\u00f4soben\u00e9ho z\u00e1palom pri lie\u010dbe infek\u010dnej peritonit\u00eddy ma\u010diek (FIP) v po\u010diato\u010dnom obdob\u00ed. Imunosupres\u00edva m\u00f4\u017eu naru\u0161i\u0165 schopnos\u0165 organizmu zotavi\u0165 sa z FIP, preto\u017ee oslabuj\u00fa prirodzen\u00e9 obrann\u00e9 syst\u00e9my zn\u00ed\u017een\u00edm z\u00e1palu a potla\u010den\u00edm imunity. To m\u00f4\u017ee vies\u0165 k zv\u00fd\u0161en\u00e9mu riziku recid\u00edvy alebo \u010fal\u0161\u00edch komplik\u00e1ci\u00ed, napr\u00edklad infekcie.<\/p>\n
Odpor\u00fa\u010danie lie\u010di\u0165 ma\u010dky s relapsom FIPGS441524 po\u010das 84 dn\u00ed je podlo\u017een\u00e9 v\u00fdskumom, ktor\u00fd ukazuje, \u017ee zvy\u0161uje \u00fa\u010dinnos\u0165 lie\u010dby. Z 393 pacientov dosiahlo 90 % \u00faspe\u0161n\u00fd priebeh pri pod\u00e1van\u00ed lieku GS441524 po\u010das 12 t\u00fd\u017ed\u0148ov a 11,4 % pred\u013a\u017eilo lie\u010dbu na viac ako 84 dn\u00ed, \u010d\u00edm dosiahlo e\u0161te lep\u0161ie v\u00fdsledky. To \u010falej posil\u0148uje d\u00f4le\u017eitos\u0165 dokon\u010denia cel\u00e9ho odpor\u00fa\u010dan\u00e9ho d\u00e1vkovania, aby sa optimalizovala miera \u00faspe\u0161nosti. Nedostato\u010dn\u00e9 d\u00e1vkovanie lieku GS441524 zvy\u0161uje riziko relapsu, ako aj rezistencie na liek, \u010do m\u00f4\u017ee v kone\u010dnom d\u00f4sledku vies\u0165 k ne\u00faspe\u0161nej lie\u010dbe v\u00e1\u0161ho ma\u010dacieho spolo\u010dn\u00edka. <\/p>\n
Po\u010das lie\u010dby relapsu FIP je nevyhnutn\u00e9 zabezpe\u010di\u0165 primeran\u00fa hydrat\u00e1ciu a v\u00fd\u017eivu. Hydrat\u00e1cia je pri lie\u010dbe ma\u010diek s FIP nesmierne d\u00f4le\u017eit\u00e1, preto\u017ee pom\u00e1ha udr\u017eiava\u0165 norm\u00e1lnu funkciu org\u00e1nov a podporuje reakciu imunitn\u00e9ho syst\u00e9mu proti v\u00edrusu. Okrem toho m\u00f4\u017ee pom\u00f4c\u0165 zn\u00ed\u017ei\u0165 niektor\u00e9 probl\u00e9my so zr\u00e1\u017ean\u00edm krvi spojen\u00e9 s t\u00fdmto ochoren\u00edm. Spr\u00e1vna v\u00fd\u017eiva pritom zohr\u00e1va z\u00e1sadn\u00fa \u00falohu pri podpore lie\u010dby a zotavenia. Primeran\u00fd pr\u00edjem bielkov\u00edn je potrebn\u00fd na vybudovanie svalov postihnut\u00fdch infekciou a obnovenie stratenej hladiny energie v d\u00f4sledku oslaben\u00e9ho stavu alebo ved\u013eaj\u0161\u00edch \u00fa\u010dinkov liekov, zatia\u013e \u010do niektor\u00e9 v\u00fd\u017eivov\u00e9 doplnky by mohli pom\u00f4c\u0165 \u010falej posilni\u0165 imunitu ma\u010dky v boji proti v\u00edrusu. <\/p>\n
Ak sa po lie\u010dbe FIP u ma\u010diek vyskytne relaps, je potrebn\u00e9 zv\u00fd\u0161i\u0165 d\u00e1vku GS441524 o 50 %. Vy\u0161\u0161ia d\u00e1vka m\u00f4\u017ee ma\u0165 lep\u0161iu \u00fa\u010dinnos\u0165 pri lie\u010dbe relapsov FIP. Ak sa u va\u0161ej ma\u010dky vyvinula vysok\u00e1 rezistencia na GS441524, m\u00f4\u017eete lie\u010dbu kombinova\u0165 s GC376. Ke\u010f v\u0161ak d\u00f4jde k relapsom, \u0161anca, \u017ee ma\u010dka pre\u017eije, je zvy\u010dajne mal\u00e1.<\/p>\n","protected":false},"excerpt":{"rendered":"
Pre\u010do doch\u00e1dza k recid\u00edve FIP? FIP je sp\u00f4soben\u00e1 v\u00edrusom, tak\u017ee choroba m\u00f4\u017ee zosta\u0165 latentn\u00e1 (neakt\u00edvna) v organizme infikovanej ma\u010dky aj nejak\u00fd \u010das po prvej lie\u010dbe. K relapsu FIP m\u00f4\u017ee d\u00f4js\u0165 aj nieko\u013eko mesiacov alebo t\u00fd\u017ed\u0148ov po ukon\u010den\u00ed lie\u010dby, ak sa v\u00edrus reaktivuje. Okrem toho sa zistilo, \u017ee relapsy s\u00fa \u010dastej\u0161ie u ma\u010diek s neurologick\u00fdmi […]<\/p>\n","protected":false},"author":1,"featured_media":28466,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_glsr_average":0,"_glsr_ranking":0,"_glsr_reviews":0,"footnotes":""},"categories":[1175],"tags":[],"_links":{"self":[{"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/pages\/28465"}],"collection":[{"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/comments?post=28465"}],"version-history":[{"count":0,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/pages\/28465\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/media\/28466"}],"wp:attachment":[{"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/media?parent=28465"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/categories?post=28465"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fipmed.co\/sk\/wp-json\/wp\/v2\/tags?post=28465"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}